TGF-beta/Smad
Hippo (MST)
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Product name : SAG
Product No. : cs-1655
Price : 50mg, $675; 100mg, $1175
CAS :
Bulk inquiry :
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| Details: |
SAG (CAS: 912545-86-9) is a potent Smoothened (Smo) receptor agonist (Kd = 59 nM); potently activates the Hedgehog signaling pathway in Shh-light 2 cells (EC50 ~ 3 nM). he Smoothened receptor (SMO) mediates signal transduction in the hedgehog pathway, which is implicated in normal development and carcinogenesis. SMO antagonists can suppress the growth of some tumours.
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