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Products > Protein Tyrosine Kinase/RTK > c-Met inhibitor > BMS817378 (BMS-817378, BMS 817378, BMS777607, BMS-777607, BMS 777607)
BMS817378 (BMS-817378, BMS 817378, BMS777607, BMS-777607, BMS 777607)
Product name : BMS817378 (BMS-817378, BMS 817378, BMS777607, BMS-777607, BMS 777607)
Product No. : cs-1639
Price : 100mg, $675, 500mg/$1875
CAS : 
Bulk inquiry : 
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  Details:
 BMS-777607 (CAS: 1025720-94-8; (old CAS#1196681-44-3)) a Met tyrosine kinase inhibitor, is an inhibitor of MET tyrosine kinase with potential antineoplastic activity. MET tyrosine kinase inhibitor BMS-777607 binds to c-Met protein, or hepatocyte growth factor receptor (HGFR), preventing binding of hepatocyte growth factor (HGF) and disrupting the MET signaling pathway; this agent may induce cell death in tumor cells expressing c-Met. c-Met, a receptor tyrosine kinase overexpressed or mutated in many tumor cell types, plays an important role in tumor cell proliferation, survival, invasion, and metastasis, and in tumor angiogenesis.

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