TGF-beta/Smad
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Product name : BIIB021 (BIIB-021)
Product No. : 2016617224411
Price : 100mg, $475, 500mg/$1275
CAS :
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| Details: |
BIIB021 (CAS: 848695-25-0) is an orally available, fully synthetic small-molecule inhibitor of HSP90 with Ki and EC50 of 1.7 nM and 38 nM, respectively. BIIB021 specifically blocks active HSP90, inhibiting its chaperone function and promoting the degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival; this may result in the inhibition of cellular proliferation in susceptible tumor cell populations.
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