TGF-beta/Smad
Nampt
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Product name : E 64d (Aloxistatin, NSC694281, Loxistatin)
Product No. : cs-1622
Price : 50mg, $675; 100mg, $1175
CAS :
Bulk inquiry :
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| Details: |
Aloxistatin (CAS: 88321-09-9), is a selective cysteine protease inhibitor or calpain and autophagy inhibitor. E-64d prevents in vitro cerulein- induced trypsinogen activation. E-64d can enter the intact cell and inhibit calpain. E-64d has been shown safe for the treatment of Alzheimer's disease in human. E-64d is potentially useful in the treatment of developmental seizure-induced brain damage both by regulating abnormal zinc signal transduction and through the modulation of altered lipid metabolism via ApoE/clusterin pathway in hippocampus.
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