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Products > Cell Cycle/DNA Damage > CDK > TG003 (TG-003)
TG003 (TG-003)
Product name : TG003 (TG-003)
Product No. : 2016617225844
Price : 100mg, $475, 500mg/$1275
CAS : 
Bulk inquiry : 
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  Details:
 TG003 (CAS: 300801-52-9)  is a potent and ATP-competitive Cdc2-like kinase (Clk) inhibitor with IC50 of 20 nM, 200 nM, and 15 nM for Clk1, Clk2, and Clk4, respectively. No inhibitory effect on Clk3, SRPK1, SRPK2, or PKC. Cdc2-like kinase (Clk), among a number of other kinases, phosphorylates serine/arginine-rich proteins which play a role in alternative splicing of pre-mRNA. 

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