Product name : NIBR-189 (NIBR189, NIBR 189)
Product No. : cs-1583
Price : 100mg, $475, 500mg/$1275
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NIBR189 (CAS: 1599432-08-2) is a small molecule antagonist of the Epstein-Barr virus-induced gene 2 (EBI2; GPR183) receptor with IC50 of 16 nM(Binding) and 11 nM (Functional). NIBR-189 blocks migration of a monocyte cell line called U937, suggesting a functional role of the oxysterol/EBI2 pathway in these immune cells.
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