Product name : VR23 (VR-23, VR 23)
Product No. : cs-1579
Price : 100mg, $475, 500mg/$1275
CAS :
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VR23 (CAS: 1624602-30-7) is a small molecule that potently inhibited the activities of trypsin-like proteasomes (IC50 = 1 nM), chymotrypsin-like proteasomes (IC50 = 50-100 nM), and caspase-like proteasomes (IC50 = 3 μM). VR23 was structurally distinct from other known proteasome inhibitors and selectively killed cancer cells by apoptosis, with little effect on noncancerous cells.
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