TGF-beta/Smad
PTEN
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Product name : VE-822 (VE822, VE 822, VX970, VX-970)
Product No. : cs-1487
Price : 100mg, $475, 500mg/$1275
CAS :
Bulk inquiry :
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| Details: |
VE-822 (CAS: 1232416-25-9) is a selective ATR inhibitor with an Ki value of 0.2 nM, >150 fold selectivity over ATM (Ki=34 nM), DNA-PK (Ki >4 uM) and mTOR (Ki >1 uM). VE-822 decreased maintenance of cell-cycle checkpoints, increased persistent DNA damage and decreased homologous recombination in irradiated cancer cells.
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