TGF-beta/Smad
c-Met inhibitor
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Product name : SU 1498 (SU1498, SU-1498)
Product No. : cs-1481
Price : 100mg, $675, 500mg/$1875
CAS :
Bulk inquiry :
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| Details: |
SU 1498 (CAS: 168835-82-3) is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2 (VEGFR2, aka FLK1; IC50 = 700 nM), having negligible activity at several other serine/threonine and tyrosine kinases. It effectively blocks signaling through VEGFR2 both in vitro and in vivo. SU 1498 is used to study the role of VEGFR2 signaling in diverse processes, including angiogenesis, tumor growth, neural progenitor cell survival, and neuroregeneration. |
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