TGF-beta/Smad
MNK
Products > MAPK/ERK Pathway > MEK > RO 4987655 (RO-4987655; RO4987655; CH-4987655; CH4987655; CH 4987655)
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Product name : RO 4987655 (RO-4987655; RO4987655; CH-4987655; CH4987655; CH 4987655)
Product No. : cs-1468
Price : 50mg, $675; 100mg, $1175
CAS :
Bulk inquiry :
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| Details: |
RO4987655(CAS: 874101-00-5) is an orally active small molecule, targeting mitogen-activated protein kinase kinase 1 (MAP2K1/MEK1 IC50=5.2 nM), with potential antineoplastic activity. MEK, a dual specificity threonine/tyrosine kinase, is a key component of the RAS/RAF/MEK/ERK signaling pathway that regulates cell growth; constitutive activation of this pathway has been implicated in many cancers.
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