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Products > Cell Cycle/DNA Damage > Checkpoint Kinase (ChK) > LY2606368 (LY-2606368, LY 2606368, Prexasertib)
LY2606368 (LY-2606368, LY 2606368, Prexasertib)
Product name : LY2606368 (LY-2606368, LY 2606368, Prexasertib)
Product No. : cs-1453
Price : 50mg, $675; 100mg, $1175
CAS : 
Bulk inquiry : 
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  Details:
 LY2606368 2HCl (CAS: 1234015-52-1) is a potent and selective ATP competitive inhibitor(IC50=1.5 nM in SW1990 cell) of the Chk1 protein kinase. LY2606368 selectively binds to chk1, thereby preventing activity of chk1 and abrogating the repair of damaged DNA. This may lead to an accumulation of damaged DNA and may promote genomic instability and apoptosis

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