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Products > Cell Cycle/DNA Damage > HDAC > ACY-1215 (ACY1215, Ricolinostat)
ACY-1215 (ACY1215, Ricolinostat)
Product name : ACY-1215 (ACY1215, Ricolinostat)
Product No. : cs-582
Price : 100mg, $475, 500mg/$975
CAS : 
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  Details:
 Rocilinostat (CAS: 1316214-52-4) is a selective HDAC6 inhibitor with IC50 of 5 nM; >10-fold more selective for HDAC6 than HDAC1/2/3 (class I HDACs) with slight activity against HDAC8, minimal activity against HDAC4/5/7/9/11, Sirtuin1, and Sirtuin2. This leads to an accumulation of unfolded and misfolded ubiquitinated proteins and may eventually induce cancer cell apoptosis, and inhibition of cancer cell growth. 

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