TGF-beta/Smad
Phospholipase
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Product name : PTC 209 (PTC-209, PTC209)
Product No. : cs-1315
Price : 100mg, $475, 500mg/$1275
CAS : 315704-66-6
Bulk inquiry : contact sales@cckinase.com for bulk inquiry
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PTC-209 (CAS: 315704-66-6) is a potent BMI-1 inhibitor with potential anticancer activity. PTC-209 inhibits endogenous BMI-1 expression in human colorectal HCT116 and human fibrosarcoma HT1080 tumor cells. PTC-209 decreases colorectal tumor cell growth in a BMI-1-dependent way. In addition, PTC-209 impairs colorectal cancer-initiating cells (CICs) through irreversible growth inhibition.
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