Product name : CP-640186 HCl (CP640186, CP 640186)
Product No. : cs-1253
Price : 100mg, $475, 500mg/$1275
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CP-640186 HCl (591778-70-0 (HCl salt); 591778-68-6 (free base)) is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively. CP-640186 can reduce body fat mass and body weight, and improve insulin sensitivity, validating ACCs as targets for antiobesity and antidiabetes drugs.
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