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Products > Others > Others > XEN-445 (XEN445, XEN 445)
XEN-445 (XEN445, XEN 445)
Product name : XEN-445 (XEN445, XEN 445)
Product No. : cs-1251
Price : 100mg, $675, 500mg/$1875
CAS : 
Bulk inquiry : 
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  Details:
XEN445 (CAS: 1515856-92-4) is potent and selective endothelial lipase inhibitor, that showed good ADME and PK properties, and demonstrated in vivo efficacy in raising plasma HDLc concentrations in mice. Endothelial lipase (EL) activity has been implicated in HDL metabolism and in atherosclerotic plaque development; inhibitors are proposed to be efficacious in the treatment of dyslipidemia related cardiovascular disease. 

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