TGF-beta/Smad
Nampt
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Product name : Seviteronel (VT-464, VT464, VT 464)
Product No. : cs-1247
Price : 50mg, $675; 100mg, $1175
CAS :
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| Details: |
VT-464 (CAS: 1610537-15-9) is a potent CYP17 lyase inhibitor(h-Lyase IC50=69 nM) that demonstrated both exceptional in vitro lyase/hydroxylase selectivity (~10-fold) and oral activity in a hamster model of androgen biosynthesis inhibition .VT-464 selectively inhibits the enzymatic activity of the cytochrome P450 C17,20 lyase in both the testes and adrenal glands, thereby inhibiting androgen production.
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