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Products > GPCR/G protein > Ras > EHT-1864 (EHT1864, EHT 1864)
EHT-1864 (EHT1864, EHT 1864)
Product name : EHT-1864 (EHT1864, EHT 1864)
Product No. : cs-1239
Price : 100mg, $875, 500mg/$2475
CAS : 
Bulk inquiry : 
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  Details:
EHT-1864 (CAS: 754240-09-0) is a potent Rac family GTPase inhibitor with Kd of 40 nM, 50 nM, 60 nM and 250 nM for Rac1, Rac1b, Rac2 and Rac3, respectively. EHT 1864 attenuates glucose-stimulated insulin secretion in pancreatic β-cells. EHT 1864 specifically inhibits glucose-induced Rac1 activation and membrane association and associated downstream signaling events culminating in inhibition of GSIS.

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