Product name : AP-1903 (AP1903, AP 1903)
Product No. : cs-1237
Price : 50mg, $675; 100mg, $1175
CAS :
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AP1903 (CAS: 195514-63-7) is a homodimer binding to FKBP; elicites potent and dosedependent apoptotic death of engineered cell line HT1080 in culture with an EC50 of 0.1 nM. This agent is used to homodimerize the Fv-containing drug-binding domains of genetically engineered receptors such as the iCD40 receptor of the autologous dendritic cell vaccine BP-GMAX-CD1, resulting in receptor activation.
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