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Products > Protein Tyrosine Kinase/RTK > FGFR > Erdafitinib (JNJ42756493, JNJ-42756493, JNJ 42756493)
Erdafitinib (JNJ42756493, JNJ-42756493, JNJ 42756493)
Product name : Erdafitinib (JNJ42756493, JNJ-42756493, JNJ 42756493)
Product No. : 201721102821
Price : 100mg, $475, 500mg/$1275
CAS : 
Bulk inquiry : 
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  Details:
Erdafitinib (CAS: 1346242-81-6) is a quinoxaline derivative compound, acts on FGFR1/2/3/4 with mean pIC50 of ~ 9/8.5/8.5/8.25, respectively. NJ-42756493 binds to and inhibits FGFR, which may result in the inhibition of FGFR-related signal transduction pathways and thus the inhibition of tumor cell proliferation and tumor cell death in FGFR-overexpressing tumor cells. FGFR, upregulated in many tumor cell types, is a receptor tyrosine kinase essential to tumor cell proliferation, differentiation and survival.

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