TGF-beta/Smad
Phospholipase
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Product name : BDA-366 (BDA366, BDA 366)
Product No. : cs-2291
Price : 100mg, $975, 500mg/$2475
CAS :
Bulk inquiry :
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| Details: |
BDA-366 (CAS: 1821496-27-8) is a BCL2-BH4 antagonist. BDA-366 suppresses human myeloma growth. BDA-366 induces robust apoptosis in MM cell lines and primary MM cells by inducing BCL2 conformational change. Delivery of BDA-366 substantially suppressed the growth of human MM xenografts in NOD-scid/IL2Rγnull mice, without significant cytotoxic effects on normal hematopoietic cells or body weight.
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