TGF-beta/Smad
Nampt
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Product name : LXR-623 (LXR623, WAY-252623, WAY 252623)
Product No. : cs-758
Price : 100mg, $475, 500mg/$1275
CAS :
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| Details: |
LXR-623 (CAS: 875787-07-8) is a highly brain-penetrant LXRα-partial/LXRβ-full agonist, with IC50 of 179 and 24 nM for LXR-β and the LXR-α subtype, respectively. It demonstrated efficacy for reducing lesion progression in the murine LDLR(-/-) atherosclerosis model with no associated increase in hepatic lipogenesis either in this model or Syrian hamsters.
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