TGF-beta/Smad
Histone Acetyltransferase (HATs)
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Product name : SGC-2085 (SGC2085, SGC 2085)
Product No. : 20171254155
Price : 100mg/$675; 500mg/$1875
CAS :
Bulk inquiry :
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| Details: |
SGC2085 (CAS: 1821908-49-9 (HCl), 1821908-48-8) is a potent and selective coactivator associated arginine methyltransferase 1 (CARM1) inhibitor with an IC50 of 50 nM. CARM1 is an important positive modulator of Wnt/β-catenin transcription and neoplastic transformation in colorectal cancer as well as a critical factor in estrogen-stimulated breast cancer growth, and its depletion results in decreased proliferation of myeloid leukemia cells in vivo.
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