TGF-beta/Smad
Salt-inducible Kinase (SIK)
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Product name : BX-471 (BX471, BX 471)
Product No. : cs-1299
Price : 100mg, $675, 500mg/$1875
CAS :
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| Details: |
BX471 (CAS: 217645-70-0 (free base), 288262-96-4 (HCl salt) is a potent, selective non-peptide CCR1 antagonist (Ki = 1 nM for human CCR1); exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4. BX-471 is the lead in a series of non-peptide chemokine receptor 1 (CCR1) antagonists, for the potential treatment of autoimmune diseases, in particular multiple sclerosis (MS).
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