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Products > Others > > Rolapitant (SCH-619734, SCH619734, SCH 619734)
Rolapitant (SCH-619734, SCH619734, SCH 619734)
Product name : Rolapitant (SCH-619734, SCH619734, SCH 619734)
Product No. : 201721532752
Price : 100mg, $675, 500mg/$1875
CAS : 
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  Details:
Rolapitant (CAS 552292-08-7 (free base), 914462-92-3 (HCl)) is an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity. Upon oral administration, rolapitant competitively binds to and blocks the activity of the NK1-receptor in the central nervous system, thereby inhibiting the binding of the endogenous ligand, substance P (SP). This may prevent both SP-induced emesis and chemotherapy-induced nausea and vomiting (CINV).

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