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Products > Protein Tyrosine Kinase/RTK > Trk Receptor > Larotrectinib (ARRY470; ARRY-470; ARRY 470; LOXO 101; LOXO101)
Larotrectinib (ARRY470; ARRY-470; ARRY 470; LOXO 101; LOXO101)
Product name : Larotrectinib (ARRY470; ARRY-470; ARRY 470; LOXO 101; LOXO101)
Product No. : cs-2322
Price : 100mg, $475, 500mg/$1275
CAS : 
Bulk inquiry : 
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  Details:
LOXO-101 (CAS: 1223403-58-4) is a potent, ATP competitive TRK inhibitor with IC50s in low nanomolar range for inhibition of all TRK family members in binding and cellular assays, with 100x selectivity over other kinases, with 2 to 20 nM cellular potency against the TRKA, TRKB, and TRKC kinases.

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