TGF-beta/Smad
PROTAC
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Product name : BMS-911543 (BMS911543, BMS 911543)
Product No. : cs-785
Price : 100mg, $675, 500mg/$1875
CAS :
Bulk inquiry :
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| Details: |
BMS-911543 (CAS: 1271022-90-2) is an orally available small molecule targeting a subset of Janus-associated kinase (JAK) with potential antineoplastic activity. BMS-911543 selectively inhibits JAK2, thereby preventing the JAK/STAT (signal transducer and activator of transcription) signaling cascade, including activation of STAT3. This may lead to an induction of tumor cell apoptosis and a decrease in cellular proliferation.
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