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Products > Epigenetics > Epigenetic Reader Domain inhibitor > PLX-51107 (PLX51107, PLX 51107)
PLX-51107 (PLX51107, PLX 51107)
Product name : PLX-51107 (PLX51107, PLX 51107)
Product No. : 20184281305
Price : 10mg/$125, 100mg/$975
CAS : 
Bulk inquiry : 
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  Details:
PLX51107 (CAS: 1627929-55-8, 10mg/$125, 100mg/$975) is a potent and selective BRD4 inhibitor or BET inhibitor with novel in vitro and in vivo pharmacologic properties that emulates or exceeds the efficacy of BCR signaling agents in preclinical models of CLL. PLX51107 binds to the acetylated lysine recognition motifs in the bromodomains of the BRD4 protein, thereby preventing the binding of BRD4 to acetylated lysines on histones. This disrupts chromatin remodeling and gene expression.

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