PKC
Metabolism
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Product name : SB-431542 (SB431542, SB- 31542)
Product No. : 2020723105841
Price : 500mg/$875
CAS : 301836-41-9
Bulk inquiry : contact sales@cckinase.com for bulk inquiry
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SB-431542 (CAS: 301836-41-9) blocked the phosphorylation and nuclear translocation of the SMADs, intracellular mediators of TGF-beta signaling, with decreased TGF-beta-mediated transcription. SB-431542 is a potent and selective inhibitor of ALK5/TGF-β type I Receptor with an IC50 value of 94 nM.
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