TGF-beta/Smad
EZH2
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Product name : BRD-73954 (BRD73954, BRD 73954)
Product No. : cs-1777
Price : 100mg, $675, 500mg/$1875
CAS :
Bulk inquiry :
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| Details: |
BRD73954 (CAS: 1440209-96-0) is a a potent and selective HDAC inhibitor with IC50 of 36 nM and 120 nM for HDAC6 and HDAC8, respectively. It inhibits HDAC6, a class IIb histone that deacetylates cytoplasmic proteins, including tubulin, heat shock protein 90, and cortactin, and has roles in cell adhesion and motility. It is also an inhibitor of HDAC8, a class I histone that primarily targets nuclear proteins, including histones and cohesins, and regulates gene expression.
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