TGF-beta/Smad
PTEN
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Product name : Vistusertib (AZD2014, AZD-2014)
Product No. : 201661723427
Price : 100mg, $475, 500mg/$975
CAS :
Bulk inquiry :
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| Details: |
AZD2014 (CAS: 1009298-59-2) is a novel mTOR inhibitor with IC50 of 2.8 nM; highly selective against multiple PI3K isoforms (α/β/γ/δ). mTOR kinase inhibitor AZD2014 inhibits the activity of mTOR, which may result in the induction of tumor cell apoptosis and a decrease in tumor cell proliferation. mTOR, a serine/threonine kinase that is upregulated in a variety of tumors, plays an important role downstream in the PI3K/Akt/mTOR signaling pathway.
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