TGF-beta/Smad
VEGFR
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Product name : BMS754807 (BMS-754807)
Product No. : 201661843324
Price : 100mg, $475, 500mg/$1275
CAS :
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| Details: |
BMS-754807 (CAS: 1001350-96-4) is a potent and reversible inhibitor of IGF-1R/InsR with IC50 of 1.8 nM/1.7 nM, less potent to Met, Aurora A/B, TrkA/B and Ron, and shows little activity to Flt3, Lck, MK2, PKA, PKC etc. inhibition of IGF-1R-mediated signaling pathways may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis.
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