TGF-beta/Smad
EZH2
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Product name : GSK 923295 (GSK-923295, GSK923295)
Product No. : cs-1336
Price : 100mg, $675, 500mg/$1875
CAS :
Bulk inquiry :
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| Details: |
GSK923295 (CAS: 1088965-37-0) is a first-in-class, specific allosteric inhibitor of CENP-E kinesin motor ATPase with Ki of 3.2 nM, and less potent to mutant I182 and T183. GSK923295A demonstrated significant antitumor activity against solid tumor models, inducing CRs in Ewing sarcoma, rhabdoid, and rhabdomyosarcoma xenografts.
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