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Products > Cell Cycle/DNA Damage > BET bromodomain > AZD-5153 (AZD5153, AZD-5153)
AZD-5153 (AZD5153, AZD-5153)
Product name : AZD-5153 (AZD5153, AZD-5153)
Product No. : 20174191420
Price : 100mg, $675, 500mg/$1875
CAS : 
Bulk inquiry : 
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  Details:
AZD5153 (CAS: 1869912-39-9) is a potent bivalent triazolopyridazine based Bromodomain and Extraterminal (BET) Inhibitor. AZD5153 exhibited excellent pharmacokinetic profile and exhibited high potency in vitro and in vivo effecting c-Myc downregulation and tumor growth inhibition in xenograft studies. AZD5153 showed enhanced potency as a result of bivalent binding and a clear correlation between BRD4 activity and cellular potency. 

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