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Products > Cell Cycle/DNA Damage > BET bromodomain > Mivebresib (ABBV-075; ABBV075; ABBV 075)
Mivebresib (ABBV-075; ABBV075; ABBV 075)
Product name : Mivebresib (ABBV-075; ABBV075; ABBV 075)
Product No. : cs-2464
Price : 100mg, $675, 500mg/$1875
CAS : 
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  Details:
Mivebresib (CAS: 1445993-26-9) is a potent BET inhibitor (bromodomain (BRD)-containing proteind) with potential antineoplastic activity. Upon administration, tABBV-075 binds to the acetyl-lysine binding site in the BRD of certain BRD-containing protein(s), thereby preventing the interaction between those proteins and acetylated histones. This disrupts chromatin remodeling, prevents the expression of certain growth-promoting genes, and leads to an inhibition of cell growth in susceptible tumors.

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