TGF-beta/Smad
EZH2
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Product name : Romidepsin (FK 228; FR 901228; NSC 630176)
Product No. : cs-972
Price : 50mg, $975; 100mg, $1475
CAS :
Bulk inquiry :
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| Details: |
Romidepsin (CAS: 128517-07-7) is a potent HDAC1 and HDAC2 inhibitor with IC50 of 36 nM and 47 nM, respectively. After intracellular activation, romidepsin binds to and inhibits histone deacetylase (HDAC), resulting in alterations in gene expression and the induction of cell differentiation, cell cycle arrest, and apoptosis.
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