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Products > Protein Tyrosine Kinase/RTK > ALK > Brigatinib (AP26113, AP-26113)
Brigatinib (AP26113, AP-26113)
Product name : Brigatinib (AP26113, AP-26113)
Product No. : cs-2153
Price : 200mg, $475, 500mg/$975
CAS : 
Bulk inquiry : 
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  Details:
 AP 26113 (CAS: 1197953-54-0) is a highly potent and selective investigational ALK inhibitor with mean IC50 value < 100 nM in Ba/F3 cells.  In addition, AP26113 appears to overcome mutation-based resistance. ALK belongs to the insulin receptor superfamily and plays an important role in nervous system development; ALK dysregulation and gene rearrangements are associated with a series of tumors. EGFR is overexpressed in a variety of cancer cell types.

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