TGF-beta/Smad
PTEN
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Product name : KU-0060648 (KU0060648, KU 0060648)
Product No. : cs-768
Price : 100mg, $975, 500mg/$2475
CAS :
Bulk inquiry :
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| Details: |
KU-0060648 (CAS: 881375-00-4) is a dual inhibitor of DNA-PK and PI-3K. KU-0060648 inhibited cellular DNA-PK autophosphorylation with IC(50) values of 0.019 μmol/L (MCF7 cells) and 0.17 μmol/L (SW620 cells), and PI-3K-mediated AKT phosphorylation with IC(50) values of 0.039 μmol/L (MCF7 cells) and more than 10 μmol/L (SW620 cells).
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