TGF-beta/Smad
PTEN
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Product name : AZ-32 (AZ32, AZ 32)
Product No. : 201810113596
Price : 10mg/$125, 100mg/$775, 500mg/$2475
CAS :
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| Details: |
AZ32 (10mg/$125, 100mg/$775) is an orally bioavailable and blood-brain barrier-penetrating ATM inhibitor with an IC50 of <6.2 nM for ATM enzyme, and an IC50 of 0.31 μM for ATM in cell. AZ32 is the first ATMi with oral bioavailability shown to radiosensitize glioma and improve survival in orthotopic mouse models.
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