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Products > Cell Cycle/DNA Damage > HMTase > PFI-2 (PFI2, PFI 2)
PFI-2 (PFI2, PFI 2)
Product name : PFI-2 (PFI2, PFI 2)
Product No. : cs-1808
Price : 100mg, $675, 500mg/$1875
CAS : 
Bulk inquiry : 
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  Details:
 PFI-2 (CAS: 1627607-87-7) is a a first-in-class, potent, highly selective, and cell-active inhibitor of the methyltransferase activity of SETD7 with IC50 of 2 nM, 500 fold active than (S)-PFI-2. Treatment of low-density MEFs with (R)-PFI-2 resulted in higher nuclear YAP levels indicating an effect on the Hippo pathway. 

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