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Products > Protein Tyrosine Kinase/RTK > ALK > X-396 (X396; X 396; Ensartinib)
X-396 (X396; X 396; Ensartinib)
Product name : X-396 (X396; X 396; Ensartinib)
Product No. : cs-1720
Price : 100mg, $675, 500mg/$1875
CAS : 
Bulk inquiry : 
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  Details:
 Ensartinib (CAS: 1365267-27-1; 1370651-20-9) is an orally available small molecule inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) with potential antineoplastic activity. Upon oral administration, X-396 binds to and inhibits ALK kinase, ALK fusion proteins and ALK point mutation variants. Inhibition of ALK leads to the disruption of ALK-mediated signaling and eventually inhibits tumor cell growth in ALK-expressing tumor cells. ALK belongs to the insulin receptor superfamily and plays an important role in nervous system development.  

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