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Products > Protein Tyrosine Kinase/RTK > Bcr-Abl > Radotinib (IY5511, IY 5511, IY-5511)
Radotinib (IY5511, IY 5511, IY-5511)
Product name : Radotinib (IY5511, IY 5511, IY-5511)
Product No. : cs-1712
Price : 100mg, $475, 500mg/$1275
CAS : 
Bulk inquiry : 
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  Details:
 Radotinib (CAS: 926037-48-1) is an orally available, a second-generation tyrosine kinase inhibitor of Bcr-Abl fusion protein and the platelet-derived growth factor receptor (PDGFR), with potential antineoplastic activity. Upon administration, radotinib specifically inhibits the Bcr-Abl fusion protein, an abnormal enzyme expressed in Philadelphia chromosome-positive chronic myeloid leukemia (CML) cells. In addition, this agent also inhibits PDGFR thereby blocking PDGFR-mediated signal transduction pathways. 

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