TGF-beta/Smad
MNK
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Product name : Refametinib (BAY 869766; BAY 86-97661; RDEA-119; RDEA119)
Product No. : cs-2434
Price : 100mg, $675, 500mg/$1875
CAS :
Bulk inquiry :
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| Details: |
Refametinib (CAS: 923032-37-5), is an orally bioavailable selective MEK inhibitor with potential antineoplastic activity (IC50=19 nM MEK1; IC50=47 nM MEK2). EK, a dual specificity threonine/tyrosine kinase, is a key component of the RAS/RAF/MEK/ERK signaling pathway that regulates cell growth; constitutive activation of this pathway has been implicated in many cancers.
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