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Products > MAPK/ERK Pathway > MEK > AS703026(Pimasertib, AS-703026 )
AS703026(Pimasertib, AS-703026 )
Product name : AS703026(Pimasertib, AS-703026 )
Product No. : cs-2173
Price : 100mg, $475, 500mg/$1275
CAS : 
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  Details:
 Pimasertib, also known as AS703026, SAR245509, MSC1936369B, (CAS:1236699-92-5) is a highly selective, potent, ATP non-competitive allosteric inhibitor of MEK1/2 with IC50 of 5 nM-2 μM in MM cell lines.AS703026 selectively binds to and inhibits the activity of MEK1/2, preventing the activation of MEK1/2-dependent effector proteins and transcription factors, which may result in the inhibition of growth factor-mediated cell signaling and tumor cell proliferation.

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