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Products > Cell Cycle/DNA Damage > PLK > Volasertib (BI 6727; BI-6727; BI6727)
Volasertib (BI 6727; BI-6727; BI6727)
Product name : Volasertib (BI 6727; BI-6727; BI6727)
Product No. : cs-1612
Price : 100mg, $675, 500mg/$1875
CAS : 
Bulk inquiry : 
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  Details:
 Volasertib (CAS: 755038-65-4) is a highly potent PLK1 inhibitor with an IC50 of 0.87 nM; shows 6- and 65-fold greater selectivity against Plk2 and Plk3. BI 6727 selectively inhibits Plk1, inducing selective G2/M arrest followed by apoptosis in a variety of tumor cells while causing reversible cell arrest at the G1 and G2 stage without apoptosis in normal cells. 

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